Detalhe da pesquisa
1.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity
; 56(3): 669-686.e7, 2023 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36889306
2.
EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.
Mol Cell
; 81(14): 2989-3006.e9, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34197737
3.
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc Natl Acad Sci U S A
; 120(24): e2216612120, 2023 06 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37276407
4.
Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Cell
; 139(1): 87-99, 2009 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-19804755
5.
A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs.
J Immunol
; 207(1): 344-351, 2021 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34183368
6.
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Cell
; 135(1): 97-109, 2008 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-18854158
7.
Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog.
Proc Natl Acad Sci U S A
; 116(13): 6120-6129, 2019 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30867290
8.
Mre11 complex links sister chromatids to promote repair of a collapsed replication fork.
Proc Natl Acad Sci U S A
; 115(35): 8793-8798, 2018 08 28.
Artigo
Inglês
| MEDLINE | ID: mdl-30104346
9.
RNase H eliminates R-loops that disrupt DNA replication but is nonessential for efficient DSB repair.
EMBO Rep
; 19(5)2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29622660
10.
Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast.
PLoS Genet
; 13(9): e1007013, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28922417
11.
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
EMBO J
; 33(5): 482-500, 2014 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24493214
12.
Critical Function of γH2A in S-Phase.
PLoS Genet
; 11(9): e1005517, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26368543
13.
Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif.
Proc Natl Acad Sci U S A
; 111(52): 18566-71, 2014 Dec 30.
Artigo
Inglês
| MEDLINE | ID: mdl-25512493
14.
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
EMBO J
; 35(7): 791, 2016 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27037288
15.
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Nucleic Acids Res
; 40(22): 11435-49, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23080121
16.
Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.
PLoS Genet
; 7(9): e1002271, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21931565
17.
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins.
Sci Transl Med
; 16(735): eadk1867, 2024 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38381847
18.
Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.
PLoS Genet
; 6(9): e1001138, 2010 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-20885790
19.
Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.
Sci Signal
; 16(798): eabk3516, 2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37582161
20.
Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
iScience
; 25(9): 104914, 2022 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35971553